1. 国家自然科学基金重大研究计划项目（培育）(92156020)“药物分子晶体组装的手性传递及其调控机制研究”(2022/01-2024/12)

2. 国家自然科学基金面上项目(22078191)“纳米纤维素凝胶中药物多晶型形成机理研究”(2021/01-2024/12)

3. 国家自然科学基金国际(地区)合作交流项目(22081340412)“中韩功能产品智能化与智慧生产管理”(2020/02-2021/12)

4. 国家自然科学基金面上项目(21978165)“模板介导药物纳米晶体精准组装的多尺度研究”(2020/01-2023/12)

5. 国家自然科学基金面上项目(21476136)“生物胶体中晶体的自组装及转变机理研究：以胆固醇结石为例”(2015/01-2018/12)

6. 上海市科委重点支撑项目(15430501200)“药物晶体组装与调控共性关键技术开发”(2015/11-2020/12)

7. 国家自然科学基金国际(地区)合作研究项目(GZ935)“Toward Further Understanding and Higher Efficiency of Protein Crystallization”(2014/01-2017/12)

8. 江苏省科技厅，江苏省自然科学基金项目(BK20131100)“药物分子多晶型结晶的机理及控制研究”(2013/07-2016/06)

9. 江苏省环保厅，江苏省环保科研课题(2012004)“高盐度工业废水的绿色循环处理新技术及其应用”(2012/08-2014/07)

10. 国家自然科学基金面上项目(21176102)“蛋白质分子晶体的二维自组装研究”(2012/01-2015/12)

11. 国家自然科学基金面上项目(21176215)”恶臭假单胞菌扁桃酸消旋酶催化底物多样性产生机制的研究”(2012/01-2015/12)

12. 国家自然科学基金国际(地区)合作交流项目(GZ843)“Fundamentals and Cutting-Edge Technologies of Industrial Crystallization”(2012/01-2012/12)

13.国家自然科学基金青年项目(20106010)“生物大分子结晶机理及其控制结晶技术研究”(2002/01-2004/12)

1. Lei-Lei Zhang#, Yue Xu#, Bo-Xuan Lou, Xiao-Lan Qin, Li-Juan Zhang, Xi-Jian Liu, Hai-Kuan Yuan, Yan Zhang, Sohrab Rohani, Jie Lu*. Effect of additives on preferential crystallization for the chiral resolution of citrulline: experimental, statistical, and molecular dynamics simulation studies. Crystal Growth & Design, 2022, 22(4), 2392-2406.

2. Jiang-Hao Zhang#, Bo-Xuan Lou#, Xiao-Lan Qin, Yin-Wen Li, Hai-Kuan Yuan, Li-Juan Zhang, Xi-Jian Liu, Yan Zhang, Jie Lu*. Using amphiphilic polymer micelles as the templates of antisolvent crystallization to produce drug nanocrystals. ACS Omega, 2022, 7(24), 21000−21013.

3. Jiao-Jiao Cao#, Bo-Xuan Lou#, Yue Xu#, Xiao-Lan Qin, Hai-Kuan Yuan, Li-Juan Zhang, Yan Zhang, Sohrab Rohani, Jie Lu*. Direct crystallization resolution of racemates enhanced by chiral nanorods: experimental, statistical, and quantum mechanics/molecular dynamics simulation studies. ACS Omega, 2022, 7(23), 19828−19841.

4. 王东博, 张蕾蕾, 翟晶焕, 张丽娟, 刘锡建, 朱雪焱, 陆杰*. 青霉胺结晶热力学及拆分工艺研究. 化工学报, 2021, 72(4), 1885-1894.

5. Ran-Ran Sun, Xiao-Meng Guo, Da-Wei Yang, Ya-Lin Tang, Jie Lu*, Hong-Xia Sun*. c-Myc G-quadruplex is sensitively and specifically recognized by a fluorescent probe. Talanta, 2021, 226, 122125.

6. Dong-Bo Wang, Jie Lu*, Lei-Lei Zhang, Fan-Fan Fan, Li-Juan Zhang, Xi-Jian Liu, Hai-Kuan Yuan, Xue-Yan Zhu. Experimental and molecular dynamics simulation study on the primary nucleation of penicillamine racemate and its enantiomers in the mixture solvent of water and ethanol. Industrial & Engineering Chemistry Research, 2020, 59(50), 21957−21968.

7. Jing-Jiao Sui, Ying Luo, Jing-Huan Zhai, Fan-Fan Fan, Li-Juan Zhang, Jie Lu,* Xue-Yan Zhu. Solubility measurement, model evaluation and molecular simulations of aprepitant (form I) in eight pure solvents. Journal of Molecular Liquids, 2020, 112723.

8. Xiao-Di Liu#, Hai-Kuan Yuan#*, Cheng-Cong Wang, Shuai Zhang, Li-Juan Zhang, Xi-Jian Liu, Feng-Jiao Liu, Xue-Yan Zhu, Sohrab Rohani, Chi-Bun Ching, Jie Lu*. A novel PVDF/PFSA-g-GO ultrafiltration membrane with enhanced permeation and antifouling performances. Separation and Purification Technology, 2020, 233, 116038.

9. Min-Yi Zhang#, Xi-Jian Liu#*, Qian Luo#, Qi Wang, Lin-Jing Zhao, Guo-Ying Deng, Ren-Bin Ge, Lei Zhang*, Jun-Qing Hu, Jie Lu*. Tumor environment responsive degradable CuS@mSiO2@MnO2/DOX for MRI guided synergistic chemo-photothermal therapy and chemodynamic therapy. Chemical Engineering Journal, 2020, 124450.

10. Wen-Yan Kong#, Qi Wang#, Guo-Ying Deng, Hang Zhao, Lin-Jing Zhao, Jie Lu*, Xi-Jian Liu*. Se@SiO2@Au-PEG/DOX NCs as a multifunctional theranostic agent: efficiently protect normal cells from oxidative damage during photothermal therapy. Dalton Transactions, 2020, 48(7), 2209−2217.

11. Fan-Fan Fan#, Hai-Kuan Yuan#, Yong-Hao Feng, Feng-Jiao Liu, Li-Juan Zhang, Xi-Jian Liu, Xue-Yan Zhu, Wei An, Sohrab Rohani, Jie Lu*. Molecular simulation approaches for the prediction of unknown crystal structures and solubilities of (R)- and (R,S)-crizotinib in organic solvents. Crystal Growth & Design, 2019, 19(10), 5882−5895.

12. Lan-Fang Ren#, Xi-Jian Liu#*, Tao Ji, Guo-Ying Deng, Feng-Jiao Liu, Hai-Kuan Yuan, Jing Yu, Junqing Hu, Jie Lu*. “All-in-one” theranostic agent with seven functions based on Bi-doped metal chalcogenides nanoflowers. ACS Applied Materials & Interfaces, 2019, 11(49), 45467−45478.

13. Ling Zhang, Xi-Jian Liu*, Min Zhang, Hai-Kuan Yuan, Li-Juan Zhang, Jie Lu*. Facile construction of dual functional Fe3O4@C-MoO2-Ni composites for catalysis and adsorption. Applied Surface Science, 2019, 494, 783−794.

14. Yi-Ling Zhang, Da-Jiang Mei*, Yi Yang, Wang-Zhu Cao, Yuan-Dong Wu, Jie Lu*, Zhe-Shuai Lin*. Rational design of new chalcogenide with good infrared nonlinear optical performance: SrZnSnS4. Journal of Materials Chemistry C, 2019, 7, 8556−8561.

15. Xue-Xue Fan, Ya-Nan Xu, Tian-Du Sheng, Dong-Qing Zhao, Hai-Kuan Yuan, Feng-Jiao Liu, Xi-Jian Liu, Xue-Yan Zhu, Li-Juan Zhang*, Jie Lu*. Amperometric sensor for dopamine based on surface-graphenization pencil graphite electrode prepared by in-situ electrochemical delamination. Microchimica Acta, 2019, 186, 324.

16. Guo-Chang Ma, Xi-Jian Liu*, Guo-Ying Deng, Hai-Kuan Yuan, Qiu-Gen Wang, Jie Lu*. A novel theranostic agent based on porous bismuth nanosphere for CT imaging guided combined chemo-photothermal therapy and radiotherapy. Journal of Material Chemistry B, 2018, 6, 6788−6795.

17. Shu-Ping Wu, Fan Wang, Hai-Kuan Yuan*, Li-Juan Zhang, Shi-Min Mao, Xi-Jian Liu, Njud S. Alharbi, Sohrab Rohani, Jie Lu*. Fabrication of xanthate-modified chitosan/poly(N-isopropylacrylamide) composite hydrogel for the selective adsorption of Cu(II), Pb(II) and Ni(II) metal ions. Chemical Engineering Research and Design, 2018, 139, 197−210.

18. Da-Wei Yan, Xi-Jian Liu*, Guo-Ying Deng, Hai-Kuan Yuan, Qiu-Geng Wang, Li-Juan Zhang, Jie Lu*. Facile assembling of novel polypyrrole nanocomposites theranostic agent for magnetic resonance and computed tomography imaging guided efficient photothermal ablation of tumors. Journal of Colloid and Interface Science, 2018, 530, 547−555.

19. Zhi Huang, Xi-Jian Liu*, Guo-Ying Deng, Hai-Kuan Yuan, Qiu-Gen Wang, Li-Juan Zhang, Jie Lu*. One-step assembly of CuMo2S3 nanocrystals for synergistic combination of photothermal therapy and photodynamic therapy. Dalton Transactions, 2018, 47, 5622−5629.

20. Xi-Jian Liu*, Ye-Ying Wang, Qi-Yang Yu, Guo-Ying Deng, Qian Wang, Xin-Hui Ma, Qiu-Gen Wang, Jie Lu*. Selenium nanocomposites as multifunctional nanoplatform forimaging guiding synergistic chemo-photothermal therapy. Colloids and Surfaces B: Biointerfaces, 2018, 166, 161−169.

21. Ye-Ying Wang, Xi-Jian Liu*, Guo-Ying Deng, Jian Sun, Hai-Kuan Yuan, Qi Li, Qiu-Gen Wang, Jie Lu*. Se@SiO2-FA-CuS nanocomposites for targeted delivery of DOX and nano selenium in synergistic combination of chemo-photothermal therapy. Nanoscale, 2018, 10, 2866−2875.

22. Fan Wang, Li-Juan Zhang*, Ye-Ying Wang, Xi-Jian Liu, Sohrab Rohani, Jie Lu*. Fe3O4@SiO2@CS-TETA functionalized graphene oxide for the adsorption of methylene blue (MB) and Cu (II). Applied Surface Science, 2017, 420, 970−981.

23. Ye-Ying Wang, Xi-Jian Liu*, Guo-Ying Deng, Qian Wang, Li-Juan Zhang, Qiu-Gen Wang, Jie Lu*. Multifunctional PS@CS@Au–Fe3O4–FA nanocomposites for CT, MR and fluorescence imaging guided targeted-photothermal therapy of cancer cells. Journal of Material Chemistry B, 2017, 5, 4221−4232.

24. Lan-Fang Ren, Xi-Jian Liu*, Qian Wang, Li-Juan Zhang, Guo-Ying Deng, Feng Zhou, Jie Lu*. Facile fabrication of a magnetically smart PTX-loaded Cys–Fe3O4/CuS@BSA nano-drug for imaging-guided chemo-photothermal therapy. Dalton Transactions, 2017, 46, 2204−2213.

25. Chang-Wei Xiao, Xi-Jian Liu*, Shi-Min Mao, Li-Juan Zhang, Jie Lu*. Sub-micron-sized polyethylenimine-modified polystyrene/Fe3O4/chitosan magnetic composites for the efficient and recyclable adsorption of Cu(II) ions. Applied Surface Science, 2017, 394, 378−385.

26. Jing-Huan Zhai, Zhen-Zhen Chen, Xi-Jian Liu, Li-Juan Zhang, Jie Lu*. Solubility measurement, model evaluation and thermodynamic analysis of rivaroxaban polymorphs in organic solvents. The Journal of Chemical Thermodynamics, 2017, 104, 218−229.

27. Zhi-Fang Gao, Xi-Jian Liu*, Ye-Ying Wang, Guo-Ying Deng, Feng Zhou, Qian Wang, Li-Juan Zhang, Jie Lu*. Facile one-pot synthesis of Fe3O4@chitosan nanospheres for MRI and fluorescence imaging guided chemo-photothermal combinational cancer therapy. Dalton Transactions, 2016, 45, 19519−19528.

28. Zhen-Zhen Chen, Jing-Huan Zhai, Xi-Jian Liu, Shi-Min Mao, Li-Juan Zhang, Sohrab Rohani, Jie Lu*. Solubility measurement and correlation of the form A of ibrutinib in organic solvents from 278.15 to 323.15 K. The Journal of Chemical Thermodynamics, 2016, 103, 342−348.

29. Zhi-Fang Gao, Xi-Jian Liu*, Guo-Ying Deng, Feng Zhou, Li-Juan Zhang, Qian Wang, Jie Lu*. Fe3O4@mSiO2-FA-CuS-PEG nanocomposites for magnetic resonance imaging and targeted chemo-photothermal synergistic therapy of cancer cells. Dalton Transactions, 2016, 45, 13456−13465.

30. Xi-Jian Liu*, Guo-Ying Deng, Ye-Ying Wang, Qian Wang, Zhi-Fang Gao, Yan-Gang Sun, Wen-Long Zhang, Jie Lu*, Jun-Qing Hu. A novel and facile synthesis of porous SiO2-coated ultrasmall Se particles as drug delivery nanoplatform for efficient synergistic treatment of cancer cells. Nanoscale, 2016, 8, 8536−8541.

31. Zhen-Xuan Fang, Xi-Jian Liu*, Mu-Dan Zhang, Jin-Rong Sun, Shi-Min Mao, Jie Lu*, Sohrab Rohani. A neural network approach to simulating the dynamic extraction process of L-phenylalanine from sodium chloride aqueous solutions by emulsion liquid membrane. Chemical Engineering Research and Design, 2016, 105, 188-199.

32. Mu-Dan Zhang, Zhen-Xuan Fang, Jing-Huan Zhai, Shi-Min Mao, Li-Juan Zhang*, Sohrab Rohani, Jie Lu*. Measurement and correlation of the solubility of rivaroxaban (form I) in binary mixtures of ethyl acetate with tetrahydrofuran, N,N-dimethylformamide, and N,N-dimethylacetamide from 278.15 to 318.15 K. The Journal of Chemical Thermodynamics, 2016, 94, 1−6.

33. Jin-Rong Sun, Li-Juan Zhang, Shi-Min Mao, Sohrab Rohani, Jie Lu*. Solid-liquid equilibrium of NaCl + HOCH2COONa + H2O system from (283.15 to 353.15) K. Fluid Phase Equilibria, 2016, 409, 334−340.

34. Guan Liu, Li-Juan Zhang*, Shi-Min Mao, Sohrab Rohani, Chi-Bun Ching, Jie Lu*. Zwitterionic chitosan-silica-PVA hybrid ultrafiltration membranes for protein separation. Separation and Purification Technology, 2015, 152, 55−63.

35. Zhen-Xuan Fang, Li-Juan Zhang, Si-Min Mao, Sohrab Rohani, Joachim Ulrich, Jie Lu*. Solubility measurement and prediction of clopidogrel hydrogen sulfate polymorphs in isopropanol and ethyl acetate. The Journal of Chemical Thermodynamics, 2015, 90, 71−78.

36. 刘锡建，任兰芳，陆杰. 铋掺杂的金属硫化物纳米花及其制备方法. 中国发明专利, ZL201910349442.X, 授权日期: 2021/09/17.

37. 王烨颖，刘锡建，陆杰. 一种偶联叶酸靶向的纳米复合粒子及其制备方法与应用. 中国发明专利, ZL201710092434.2, 授权日期: 2020/05/05.

38. 高志方, 刘锡建, 王烨颖, 王帆, 任兰芳, 陆杰. 偶联叶酸靶向的四氧化三铁/介孔二氧化硅/硫化铜纳米复合粒子及其制备方法和应用. 中国发明专利, ZL201610250533.4, 授权日期: 2020/04/07.

39. 马国昌，刘锡建，袁海宽，陆杰. 一种多孔铋纳米微球及其制备方法和应用. 中国发明专利, ZL201811008014.2, 授权日期: 2020/03/09.

40. 刘锡建, 陆杰, 王烨颖, 任兰芳, 邓国英, 王谦, 周峰. 一种金包覆硒化铜纳米粒子及其制备方法与应用. 中国发明专利, ZL201610557212.9, 授权日期: 2019/05/24.

41. 翟晶焕, 陈真真, 陆杰. 一种来那度胺与烟酰胺共晶的制备方法. 中国发明专利, ZL201610220805.6, 授权日期: 2018/10/26.

42. 高志方, 刘关, 陈真真, 翟晶焕, 陆杰. 一种抗蛋白质污染两性离子超滤膜及其制备方法. 中国发明专利, ZL201610136103.X, 授权日期: 2018/07/24.

43. 刘锡建, 陆杰, 孙彦刚, 张丽娟, 张红, 徐菁利. 一种多孔Se-SiO2纳米粒子及其制备方法和应用. 中国发明专利, ZL201510496173.1, 授权日期: 2017/12/29.

44. 陆杰, 林青, 周迅, 陈莲蔚, 吴丹辉. 一种制备无定形埃索美拉唑镁盐的结晶方法. 中国发明专利, ZL201310445802.9, 授权日期: 2015/01/07.

45. 陆杰, 李祯, 李义平, 汪晶. 一种制备一水合L-苯丙氨酸的结晶方法. 中国发明专利， ZL201110342607.4, 授权日期: 2014/05/21.

46. 陆杰, 汪晶, 李义平, 林青, 舒亮, 曾德利. 一种甲磺酸伊马替尼α晶型的制备方法. 中国发明专利, ZL201210098962.6, 授权日期: 2013/07/17.

47. 陆杰, 陈其林, 郭春荣, 叶勤, 李同斌. 一种从植物油脱臭馏出物中分离纯化甾醇的结晶方法. 中国发明专利, ZL200910223276.5, 授权日期: 2012/01/04.

2022 国家一流本科专业化学工程与工艺负责人

2021 全国石油和化工教育优秀教学团队负责人

2018 上海市科技进步二等奖

2014 中国轻工业联合会科技进步三等级

2013 中国商业联合会科技进步一等奖

2010 中国轻工业联合会科技进步三等级

2001 教育部“高等学校骨干教师”

社会兼职

委员：ACS、中国化工学会第1届医药化工专业委员会、中国药学会药物晶体工程小组，等

编辑：Journal of Chemical Research and Application，American Journal of Chemical Engineering，Current Chinese Science，等

评审：

中国国家基金委各类项目(2012-)

教育部博士点基金及学位与研究生教育(2013-)

上海市学位与研究生教育(2015-)

上海市科技奖励(2018-)

国家科技奖励(2019-)

上海市生态环境应急管理(2021-)

科技部各类专项与研发计划（2022-）, 等